Endocrine Abstracts

Introduction: Premature ovarian failure (POF) is defined as amenorrhea lasting more than four months before the age of 40 with a high level of gonadotropins in at least two separate samples. The aim of this work was to describe the etiological profile of a series of Tunisian women followed for POF.Patients and methods: It is a descriptive study of 42 cases of POF collected in the endocrinology department of Sousse between 2000 and 2017.<p class="abst...

Introduction: The therapeutic management of premature ovarian failure (POF) consists of a hormone replacement therapy that must be regular to avoid cardiovascular and bone complications as well as psychological management. The objective of this work was to study complications at 15 years of evolution of 42 tunisian women followed for POF.Patients and methods: It’s a retrospective study of 42 patients followed in the endocrinology department of Souss...

Introduction: Endocrine hypertension is the most common cause of secondary hypertension affecting nearly 3% of the population. Adrenal etiologies play a significant role in these cases. An adrenal incidentaloma is an asymptomatic adrenal tumor, at least one cm in diameter, discovered incidentally during a medical imaging examination. It requires an investigation into its secretory or malignant nature leading to the development of arterial hypertension.Ma...

Introduction: Primary hyperparathyroidism JawTumor Syndrome is a rare genetic disorder characterized by the synchronous or metachronous occurrence of primary hyperparathyroidism and an ossifying fibroma of the maxilla and/or mandible, associated with an increased risk of parathyroid carcinoma.Observation: We report the case of a 30-year-old young woman who consulted for a limp in walking,6 months after having been operated for a juvenile ossifying fibrom...

Wolfram syndrome is a rare, autosomal recessive entity characterized by several progressive neurodegenerative manifestations.Observation: We report the case of a 27-year-old patient from a Consanguineous marriage, followed for hypogonadism with delayed puberty and insulin-requiring diabetes since the age of 13 with negative autoantibodies. His diabetes is complicated after 5 years of a mainly vegetative neuropathy with neurogenic bladder complicated by b...

Introduction: Several studies have incriminated hypomagnesemia in the pathophysiology of diabetes, as the prevalence of this deficit in type 2 diabetics is high, and as it is correlated with glycemic control and chronic diabetic complications.Aims: Studying the prevalence of hypomagnesemia in type 2 diabetics and assessing its impact on quality of life, glycemic control and chronic diabetic complications. Patients and methods: We conducted a descriptive ...

Introduction: Verneuil’s disease, also known as Hidradenitis suppurativa, is a chronic inflammatory dermatosis characterized by recurrent episodes. It’s manifested by painful deep inflammatory nodules, comedones, and scarring in areas rich in apocrine glands. Its prevalence is estimated at 1% of the population. It is influenced by factors such as obesity, smoking, and genetics. We report the case of a patient admitted for diabetes in whom Hidradenitis suppurativa was...

Introduction: The most recent declared pandemic is attributed to COVID-19, caused by the novel coronavirus SARS-CoV-2. The angiotensin-converting enzyme 2, the principal receptor for SARS-CoV-2, exhibits expression in various tissues, prominently within gonadal and hypothalamo-hypophyseal domains. Long COVID, characterized by persistent symptoms post-infection, manifests in certain individuals and includes manifestations associated with the genitourinary system, such as sexual...

Introduction : Few studies have considered the natural history of pituitary anatomy in Sheehan syndrome (SS), as seen on magnetic resonance imaging (MRI) or CT scan. An imaging study of the sella turcica was carried out in patients with SS. The aim was to look for correlations between radiological findings and the degree of endocrine insufficiency on the one hand, and diagnosis delay on the other.Methods: This is a retrospective study carried out between...

Introduction: Macroprolactinemia is a polymeric form of prolactin release that leads to clinically paucisymptomatic presentations. It can be isolated or associated with other causes of hyperprolactinemia. We report the case of macroprolactinemia discovered in a patient being treated for an empty sella turcica.Case report: This concerns a 47-year-old patient, monitored since the age of 31 for moderate idiopathic hyperprolactinemia discovered following bil...